Complex Portal - A Unifying Protein Complex Database

  • Birgit Meldal European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
  • C. Combe Wellcome Trust Centre for Cell Biology
  • H. Bye-A-Jee European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
  • J. Heimbach Cambridge Systems Biology Centre
  • M. Koch European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
  • J. Sullivan Cambridge Systems Biology Centre
  • Y. Yehudi Cambridge Systems Biology Centre
  • G. Micklem Cambridge Systems Biology Centre
  • H. Hermjakob European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
  • P. Porras Millán European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
  • S. Orchard European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)

Abstract

The EBI Complex Portal is a manually curated, unifying resource of macromolecular complexes from model organisms. Each entry has a unique and stable identifier and links participating molecule to their unique reference database (UniProt, ChEBI and RNAcentral). Each complex is annotated with information about their stoichiometry, topology and structural assembly, function, complex-centric Gene Ontology terms and evidence codes. Complexes are extensively cross-referenced to ChEMBL, EMDB, Experimental Factor Ontology, Intenz, MatrixDB, the PDB and Reactome. Bespoke visualisation tools for the general topology and stoichiometry, crystal structures, molecular reactions and gene expression data are provided. All data is open-source and available in PSI-MI xml2.5 and xml3.0 standard formats, MI-JSON and tab-delineated ComplexTAB format.

Published
2017-12-06
How to Cite
MELDAL, Birgit et al. Complex Portal - A Unifying Protein Complex Database. Genomics and Computational Biology, [S.l.], v. 4, n. 1, p. e100052, dec. 2017. ISSN 2365-7154. Available at: <https://genomicscomputbiol.org/ojs3/GCB/article/view/52>. Date accessed: 22 may 2018. doi: https://doi.org/10.18547/gcb.2018.vol4.iss1.e100052.
Section
Short Communications